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科研成就

2020年代表作

1. Bai L#*, You Q#, Jain BK#, Duan HD, Kovach A, Graham TR, Li H*. Transport mechanism of P4 ATPase phosphatidylcholine flippases. Elife. 2020 Dec 15;9:e62163.

2. Rongcheng Han#, Miao Zhao#, Zhiwei Wang#, Helin Liu, Shengcang Zhu, Lu Huang,Yu Wang, Lijun Wang, Yuankai Hong, Yinlin Sha,* and Yuqiang Jiang*, Super-efficient in Vivo Two-Photon Photodynamic Therapy with a Gold Nanocluster as a Type I Photosensitizer. ACS Nano, 2020, 14, 9532−9544.

3. Yan XE(#), Ayaz P(#), Zhu SJ(#), Zhao P(#), Liang L, Zhang CH, Wu YC, Li JL, Choi HG, Huang X, Shan Y(*), Shaw DE(*), Yun CH(*). Structural Basis of AZD9291 Selectivity for EGFR T790M. J Med Chem. 2020 Aug 13;63(15):8502-8511. doi: 10.1021/acs.jmedchem.0c00891.

4. Yang J(#), Shibu MA(#), Kong L(#), Luo J, BadrealamKhan F, Huang Y, Tu ZC, Yun CH(*), Huang CY(*), Ding K(*), Lu X(*). Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors. J Med Chem. 2020 Mar 12;63(5):2114-2130. doi:10.1021/acs.jmedchem.9b00664.

5. Liu D#, Chen Q, Zhang L, Hu H, Yin C*. AgsA oligomer acts as a functional unit. Biochem Biophys Res Commun. 2020 Sep 10;530(1):22-28. doi: 10.1016/j.bbrc.2020.07.027.

6.Ling Liang#*, Jiawen Feng#, Peng Zuo, Juan Yang, Yishuo Lu, Yuxin Yin*, Molecular basis for assembly of the shieldin complex and its implications for NHEJ, Nature Communications, 2020, 11: 1972