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科研成就

2021年代表作

1. Zhao P#, Zhao C#, Chen D, Yun C, Li H*, Bai L*. Structure and activation mechanism of the hexameric plasma membrane H+-ATPase. Nat Commun. 2021 Nov 8;12(1):6439.

2. Bai L#*, Jain BK#, You Q#, Duan HD, Takar M, Graham TR*, Li H*. Structural basis of the P4B ATPase lipid flippase activity. Nat Commun. 2021 Oct 13;12(1):5963.

3. Bai L*, Li H*. Cryo-EM structures of the endoplasmic reticulum membrane complex. FEBS J. 2021 Feb 24. doi: 10.1111/febs.15786. (Review)

4. Bai L*, Li H*. Protein N-glycosylation and O-mannosylation are catalyzed by two evolutionarily related GT-C glycosyltransferases. Curr Opin Struct Biol. 2021 Jan 11;68:66-73. (Review)

5. Ye Tian*, Ming Wei, Lijun Wang , Yuankai Hong*, Dan Luo*, Yinlin Sha*, Two-Photon Time-Gated In Vivo Imaging of Dihydrolipoic-Acid-Decorated Gold Nanoclusters. Materials (Basel). Materials 2021, 14, 7744.

6. Sun FH(#), Zhao P(#), Zhang N, Kong LL, Wong CCL, Yun CH(*). HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones. Nat Commun. 2021 Feb 15;12(1):1028. doi: 10.1038/s41467-021-21302-4.

7. Yuan Wang#, Chunlei Zhang#, Shipeng Shao, Wenzhong Yang, Xinmin Xu, Yujie Sun, Pilong Li, Ling Liang*, Congying Wu*, LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force, Developmental Cell, 2021, 56:1-13.

8. Shi C#, Gu M#, Chen Z, Huang X, Guo J, Huang L, Deng J, Ke He, Zhang L, Huang L, Chang Z*. Structural insights revealed by crystal structures of CYP76AH1 and CYP76AH1 in complex with its natural substrate. Biochem Biophys Res Commun. 2021582:125-130.

9. Wei M, Tian Y, Wang L, Hong Y, Luo D, Sha Y*. The Emission Mechanism of Gold Nanoclusters Capped with 11-Mercaptoundecanoic Acid, and the Detection of Methanol in Adulterated Wine Model. Materials (Basel). 2021 Oct 23;14(21):6342.

10. Luo D.#*,Wang P.,Zheng Q.,Han R.,Shi C.,Wang L.,Hong Y.,Liu Y*, Sha Y*.Magnetic nanoparticle-based solid phase peptide synthesis and the synchronous detection of their biological activity.  2021, Materials Today Advances, 12,100175.DOI:10.1016/j.mtadv.2021.100175